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Anti-Human DYNLL1 Polyclonal Antibody (HX228014)

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Número de catálogoHX228014
Descripción
Anti-Human DYNLL1 Polyclonal Antibody (HX228014) is a rabbit polyclonal antibody detecting DYNLL1 in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human DYNLL1 (Cys2-Gly89).
Objetivo DNCL1, Dynein light chain 1, cytoplasmic, DNCLC1, 8 kDa dynein light chain, DLC1, HDLC1, PIN, Dynein light chain LC8-type 1, DLC8, Protein inhibitor of neuronal nitric oxide synthase, DYNLL1
Purificación Purified by antigen affinity column.
Número de acceso P63167
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Dynein light chain 1, cytoplasmic (DYNLL1) is a ~10 kDa protein. Component of dynein, a family of motor proteins essential for movement along microtubules. Required for structural and functional integrity of cilia. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.

1. Puthalakath, H. et al. (1999) Molecular cell 3, 287-96. PMID: 10198631
2. Vadlamudi, RK. et al. (2004) Cancer cell 5, 575-85. PMID: 15193260
3. Rayala, SK. et al. (2005) EMBO reports 6, 538-44. PMID: 15891768
4. Rayala, SK. et al. (2006) The Journal of biological chemistry 281, 19092-9. PMID: 16684779
5. He, YJ. et al. (2018) Nature 563, 522-526. PMID: 30464262
6. Swift, ML. et al. (2023) Nature structural & molecular biology 30, 1456-1467. PMID: 37696958
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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