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| カタログ番号 | HX228014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human DYNLL1 Polyclonal Antibody (HX228014) is a rabbit polyclonal antibody detecting DYNLL1 in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human DYNLL1 (Cys2-Gly89). | ||||||||
| ターゲット | DNCL1, Dynein light chain 1, cytoplasmic, DNCLC1, 8 kDa dynein light chain, DLC1, HDLC1, PIN, Dynein light chain LC8-type 1, DLC8, Protein inhibitor of neuronal nitric oxide synthase, DYNLL1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P63167 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Dynein light chain 1, cytoplasmic (DYNLL1) is a ~10 kDa protein. Component of dynein, a family of motor proteins essential for movement along microtubules. Required for structural and functional integrity of cilia. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. 1. Puthalakath, H. et al. (1999) Molecular cell 3, 287-96. PMID: 10198631 2. Vadlamudi, RK. et al. (2004) Cancer cell 5, 575-85. PMID: 15193260 3. Rayala, SK. et al. (2005) EMBO reports 6, 538-44. PMID: 15891768 4. Rayala, SK. et al. (2006) The Journal of biological chemistry 281, 19092-9. PMID: 16684779 5. He, YJ. et al. (2018) Nature 563, 522-526. PMID: 30464262 6. Swift, ML. et al. (2023) Nature structural & molecular biology 30, 1456-1467. PMID: 37696958 | ||||||||
| 注意事項 | For research use only. |
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