

| Número de catálogo | HT181014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human E2F3 Polyclonal Antibody (HT181014) is a rabbit polyclonal antibody detecting E2F3 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human E2F3 (Ser174-Gly250). | ||||||||
| Objetivo | E2F-3, KIAA0075, Transcription factor E2F3, E2F3 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O00716 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Transcription factor E2F3 is a ~49 kDa protein. Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters. | ||||||||
| Nota | For research use only. |


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