

| Numéro de catalogue | HT181014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human E2F3 Polyclonal Antibody (HT181014) is a rabbit polyclonal antibody detecting E2F3 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human E2F3 (Ser174-Gly250). | ||||||||
| Cible | E2F-3, KIAA0075, Transcription factor E2F3, E2F3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O00716 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Transcription factor E2F3 is a ~49 kDa protein. Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters. | ||||||||
| Note | For research use only. |


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