

| Número de catálogo | HF932014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human E2F6 Polyclonal Antibody (HF932014) is a rabbit polyclonal antibody detecting E2F6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human E2F6 (Pro62-Glu237). | ||||||||
| Objetivo | Transcription factor E2F6, E2F-6, E2F6 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O75461 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Transcription factor E2F6 is a ~31 kDa protein. Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. 1. Trimarchi, JM. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 2850-5. PMID: 9501179 2. Gaubatz, S. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 9190-5. PMID: 9689056 3. Cartwright, P. et al. (1998) Oncogene 17, 611-23. PMID: 9704927 | ||||||||
| Nota | For research use only. |
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