

| Numéro de catalogue | HF932014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human E2F6 Polyclonal Antibody (HF932014) is a rabbit polyclonal antibody detecting E2F6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human E2F6 (Pro62-Glu237). | ||||||||
| Cible | Transcription factor E2F6, E2F-6, E2F6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O75461 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Transcription factor E2F6 is a ~31 kDa protein. Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. 1. Trimarchi, JM. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 2850-5. PMID: 9501179 2. Gaubatz, S. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 9190-5. PMID: 9689056 3. Cartwright, P. et al. (1998) Oncogene 17, 611-23. PMID: 9704927 | ||||||||
| Note | For research use only. |
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