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Anti-Human EFTUD2 Polyclonal Antibody (HD650014)

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Vista general
Número de catálogoHD650014
Descripción
Anti-Human EFTUD2 Polyclonal Antibody (HD650014) is a rabbit polyclonal antibody detecting EFTUD2. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human EFTUD2 (Thr661-Met972).
Objetivo 116 kDa U5 small nuclear ribonucleoprotein component, EFTUD2, Elongation factor Tu GTP-binding domain-containing protein 2, KIAA0031, SNRP116, SNU114 homolog, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, hSNU114
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q15029
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) is a ~109 kDa protein. Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).

1. Oka, Y. et al. (2014) EMBO reports 15, 956-64. PMID: 25092792
2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346
3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770
4. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166
5. Zhan, X. et al. (2018) Science (New York, N.Y.) 359, 537-545. PMID: 29301961
6. Zhang, X. et al. (2018) Cell research 28, 307-322. PMID: 29360106
7. Haselbach, D. et al. (2018) Cell 172, 454-464.e11. PMID: 29361316
8. Zhan, X. et al. (2018) Cell research 28, 1129-1140. PMID: 30315277
9. Fica, SM. et al. (2019) Science (New York, N.Y.) 363, 710-714. PMID: 30705154
10. Liu, S. et al. (2006) RNA (New York, N.Y.) 12, 1418-30. PMID: 16723661
Nota For research use only
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Formula
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Formula
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Working Solution
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