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Anti-Human EFTUD2 Polyclonal Antibody (HD650014)

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Aperçu
Numéro de catalogueHD650014
Description
Anti-Human EFTUD2 Polyclonal Antibody (HD650014) is a rabbit polyclonal antibody detecting EFTUD2. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human EFTUD2 (Thr661-Met972).
Cible 116 kDa U5 small nuclear ribonucleoprotein component, EFTUD2, Elongation factor Tu GTP-binding domain-containing protein 2, KIAA0031, SNRP116, SNU114 homolog, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, hSNU114
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès Q15029
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Contexte

116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) is a ~109 kDa protein. Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).

1. Oka, Y. et al. (2014) EMBO reports 15, 956-64. PMID: 25092792
2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346
3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770
4. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166
5. Zhan, X. et al. (2018) Science (New York, N.Y.) 359, 537-545. PMID: 29301961
6. Zhang, X. et al. (2018) Cell research 28, 307-322. PMID: 29360106
7. Haselbach, D. et al. (2018) Cell 172, 454-464.e11. PMID: 29361316
8. Zhan, X. et al. (2018) Cell research 28, 1129-1140. PMID: 30315277
9. Fica, SM. et al. (2019) Science (New York, N.Y.) 363, 710-714. PMID: 30705154
10. Liu, S. et al. (2006) RNA (New York, N.Y.) 12, 1418-30. PMID: 16723661
Note For research use only
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Formula
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