Anti-Human EIF6 Polyclonal Antibody (HX091014)

Name: Anti-Human EIF6 Polyclonal Antibody
Brand: abinScience
SKU: HX091014
Price: 168 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HX091014

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human EIF6 (Met1-Thr245).

Objetivo

Eukaryotic translation initiation factor 6, EIF3A, eIF-6, ITGB4BP, B(2)GCN homolog, B4 integrin interactor, CAB, p27(BBP), EIF6

Purificación

Purified by antigen affinity column.

Número de acceso

P56537

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Eukaryotic translation initiation factor 6 (EIF6) is a ~26 kDa protein. Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity.

1. Sanvito, F. et al. (1999) The Journal of cell biology 144, 823-37. PMID: 10085284

2. Ceci, M. et al. (2003) Nature 426, 579-84. PMID: 14654845

3. Finch, AJ. et al. (2011) Genes & development 25, 917-29. PMID: 21536732

4. Liang, X. et al. (2020) Nature communications 11, 3542. PMID: 32669547

5. Chendrimada, TP. et al. (2007) Nature 447, 823-8. PMID: 17507929

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human EIF6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo