Anti-Human EIF6 Polyclonal Antibody (HX091014)

Name: Anti-Human EIF6 Polyclonal Antibody
Brand: abinScience
SKU: HX091014
Price: 168 USD
Availability: InStock

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50ug
100ug

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HX091014

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human EIF6 (Met1-Thr245).

Cible

Eukaryotic translation initiation factor 6, EIF3A, eIF-6, ITGB4BP, B(2)GCN homolog, B4 integrin interactor, CAB, p27(BBP), EIF6

Purification

Purified by antigen affinity column.

Numéro d'accès

P56537

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Eukaryotic translation initiation factor 6 (EIF6) is a ~26 kDa protein. Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity.

1. Sanvito, F. et al. (1999) The Journal of cell biology 144, 823-37. PMID: 10085284

2. Ceci, M. et al. (2003) Nature 426, 579-84. PMID: 14654845

3. Finch, AJ. et al. (2011) Genes & development 25, 917-29. PMID: 21536732

4. Liang, X. et al. (2020) Nature communications 11, 3542. PMID: 32669547

5. Chendrimada, TP. et al. (2007) Nature 447, 823-8. PMID: 17507929

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human EIF6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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