Please ensure Javascript is enabled for purposes of website accessibility
Contáctenos Contáctenos
ES
Inicio > Productos > Anticuerpos > Anticuerpos Primarios

Anti-Human ENPP1 Polyclonal Antibody (HB920014)

Datasheet Compartir producto Copiar información
Anti-Human ENPP1 Polyclonal Antibody
Anti-Human ENPP1 Polyclonal Antibody
Precio(USD): --
Especificación:
  • 20ug
  • 50ug
  • 100ug
Número:
Contáctenos

  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHB920014
Descripción
Anti-Human ENPP1 Polyclonal Antibody (HB920014) is a rabbit polyclonal antibody detecting ENPP1 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human ENPP1 (Asp362-Trp518).
Objetivo ENPP1
Purificación Purified by antigen affinity column.
Número de acceso P22413
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosEctonucleotide pyrophosphatase/phosphodiesterase family member 1, E-NPP 1, Membrane component chromosome 6 surface marker 1, Phosphodiesterase I/nucleotide pyrophosphatase 1, Plasma-cell membrane glycoprotein PC-1, Alkaline phosphodiesterase I, 3.1.4.1, Nucleotide pyrophosphatase, NPPase, 3.6.1.9, Nucleotide diphosphatase, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form, ENPP1, M6S1, NPPS, PC1, PDNP1
Fondo

Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) is a ~104 kDa protein. Nucleotide pyrophosphatase that generates diphosphate (PPi) and functions in bone mineralization and soft tissue calcification by regulating pyrophosphate levels. PPi inhibits bone mineralization and soft tissue calcification by binding to nascent hydroxyapatite crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP and UTP to their corresponding monophosphates with release of pyrophosphate, as well as diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling; it is however unclear whether hedgehog inhibition is direct or indirect.

1. Johnson, KA. et al. (2000) American journal of physiology. Regulatory, integrative and comparative physiology 279, R1365-77. PMID: 11004006
2. Li, L. et al. (2014) Nature chemical biology 10, 1043-8. PMID: 25344812
3. Stella, J. et al. (2016) Human mutation 37, 1190-1201. PMID: 27467858
4. Namasivayam, V. et al. (2017) Biochimica et biophysica acta. General subjects 1861, 603-614. PMID: 28011303
5. Szeri, F. et al. (2022) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 37, 1024-1031. PMID: 35147247
6. Belli, SI. et al. (1994) European journal of biochemistry 226, 433-43. PMID: 8001561
7. Maddux, BA. et al. (2000) Diabetes 49, 13-9. PMID: 10615944
8. Chourabi, M. et al. (2018) The Journal of investigative dermatology 138, 291-300. PMID: 28964717
Nota For research use only.
Imágenes
  • Anti-Human ENPP1 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-ENPP1 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: NIH3T3 cell lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recomendación

Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.

Correo: [email protected]

Lista de distribuidores

Obtener una cotización gratuita
Anti-Human ENPP1 Polyclonal Antibody

Acceso rápido

Contáctenos

  • +86-027-65523339

  • [email protected]

  • Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China

  • linkedin
  • Ins
  • youtube
  • youtube
Derechos de autor © 2026 abinScience. Todos los derechos reservados. Todos los productos son solo para uso de investigación