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| カタログ番号 | HP048137 |
|---|---|
| 種反応性 | Human |
| アプリケーション | ELISA, FCM |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2a, kappa |
| クローンID | SAA0771 |
| 抱合 | APC |
| ターゲット | Ecto-ATP diphosphohydrolase 2, Ecto-ATPDase 2, ENTPD2, CD39 antigen-like 1, Ectonucleoside triphosphate diphosphohydrolase 2, NTPDase 2, Ecto-ATPase 2, CD39L1 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC |
| アクセッション番号 | Q9Y5L3 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2/CD39L1) is a ~53 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs), with a marked preference for triphosphonucleosides over diphosphonucleosides. The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates. This activity contributes to the regulation of extracellular nucleotides levels. ATP hydrolysis is characterized by fast ADP accumulation and delayed AMP formation, reflecting limited ADP hydrolase activity. Hydrolyzes ADP and UDP only to a marginal extent, and does not hydrolyze AMP. 1. Mateo, J. et al. (1999) British journal of pharmacology 128, 396-402. PMID: 10510450 2. Mateo, J. et al. (2003) The Journal of biological chemistry 278, 39960-8. PMID: 12888562 3. Mukasa, T. et al. (2005) Biochemistry 44, 11160-70. PMID: 16101300 4. Kukulski, F. et al. (2005) Purinergic signalling 1, 193-204. PMID: 18404504 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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