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Anti-Human ENTPD2/CD39L1 Recombinant Antibody (SAA0771), PE (HP048127)

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Aperçu
Numéro de catalogueHP048127
Reactivité des espècesHuman
ApplicationsELISA, FCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de cloneSAA0771
ConjugaisonPE
Cible Ecto-ATP diphosphohydrolase 2, Ecto-ATPDase 2, ENTPD2, CD39 antigen-like 1, Ectonucleoside triphosphate diphosphohydrolase 2, NTPDase 2, Ecto-ATPase 2, CD39L1
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PE
Numéro d'accès Q9Y5L3
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2/CD39L1) is a ~53 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs), with a marked preference for triphosphonucleosides over diphosphonucleosides. The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates. This activity contributes to the regulation of extracellular nucleotides levels. ATP hydrolysis is characterized by fast ADP accumulation and delayed AMP formation, reflecting limited ADP hydrolase activity. Hydrolyzes ADP and UDP only to a marginal extent, and does not hydrolyze AMP.

1. Mateo, J. et al. (1999) British journal of pharmacology 128, 396-402. PMID: 10510450
2. Mateo, J. et al. (2003) The Journal of biological chemistry 278, 39960-8. PMID: 12888562
3. Mukasa, T. et al. (2005) Biochemistry 44, 11160-70. PMID: 16101300
4. Kukulski, F. et al. (2005) Purinergic signalling 1, 193-204. PMID: 18404504
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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