Anti-Human EP300 IP Recombinant Antibody (SAA0246) (HC510013)

Name: Anti-Human EP300 IP Recombinant Antibody (SAA0246)
Brand: abinScience
SKU: HC510013
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC510013

Reactividad de especies

Human

Aplicaciones

ELISA, IF, IP, IP-MS

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG1, kappa

ID de clon

SAA0246

Objetivo

Histone crotonyltransferase p300, Protein lactyltransferas p300, Protein propionyltransferase p300, Histone acetyltransferase p300, Protein 2-hydroxyisobutyryltransferase p300, EP300, p300 HAT, Histone butyryltransferase p300, P300, E1A-associated protein p300

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q09472

RRID

Anti-Human EP300 IP Antibody (SAA0246) (abinScience Cat# HC510013, RRID:AB_3729780)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Histone acetyltransferase p300 (EP300) is a ~264 kDa protein. Functions as a histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates acetylation of histone H3 at 'Lys-122' (H3K122ac), a modification that localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability. Mediates acetylation of histone H3 at 'Lys-18' and 'Lys-27' (H3K18ac and H3K27ac, respectively).

1. Tropberger, P. et al. (2013) Cell 152, 859-72. PMID: 23415232

2. Delvecchio, M. et al. (2013) Nature structural & molecular biology 20, 1040-6. PMID: 23934153

3. Tian, Y. et al. (2025) Nature 641, 779-787. PMID: 40240600

4. Ogryzko, VV. et al. (1996) Cell 87, 953-9. PMID: 8945521

5. Jin, Q. et al. (2011) The EMBO journal 30, 249-62. PMID: 21131905

6. Hatzi, K. et al. (2013) Cell reports 4, 578-88. PMID: 23911289

8. Iioka, T. et al. (2003) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 18, 1419-29. PMID: 12929931

9. Yuan, ZL. et al. (2005) Science (New York, N.Y.) 307, 269-73. PMID: 15653507

10. Ray, S. et al. (2005) Gastroenterology 129, 1616-32. PMID: 16285960

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human EP300 IP Antibody (SAA0246)

Referencias

Datasheet

Anti-Human EP300 IP Recombinant Antibody (SAA0246).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo