

| Número de catálogo | HX086014 | ||||||||
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| Descripción |
Anti-Human EPHB4 Polyclonal Antibody (HX086014) is a rabbit polyclonal antibody detecting EPHB4. Suitable for Human.
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human EPHB4 (Leu16-Ala539). | ||||||||
| Objetivo | EC:2.7.10.1, EPHB4, Ephrin type-B receptor 4, HTK, Hepatoma transmembrane kinase, MYK1, TYRO11, Tyrosine-protein kinase TYRO11 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P54760 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Ephrin type-B receptor 4 (EPHB4) is a ~108 kDa protein. Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. | ||||||||
| Nota | For research use only |



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