

| Número de catálogo | HB152137 |
|---|---|
| Reactividad de especies | Human |
| Aplicaciones | FCM |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | ABT-007 |
| Conjugación | APC |
| Objetivo | EPOR, Erythropoietin receptor, EPO-R |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Productos asociados | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC |
| Número de acceso | P19235 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Fondo | Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. 1. Zhan, H. et al. (1999) Protein engineering 12, 505-13. PMID: 10388848 2. Winkelmann, JC. et al. (1990) Blood 76, 24-30. PMID: 2163695 3. Jones, SS. et al. (1990) Blood 76, 31-5. PMID: 2163696 4. Middleton, SA. et al. (1996) The Journal of biological chemistry 271, 14045-54. PMID: 8662939 5. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 6. Kirito, K. et al. (2002) Blood 99, 102-10. PMID: 11756159 |
| Nota | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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