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Anti-Human Erythropoietin R Recombinant Antibody (ABT-007), APC (HB152137)

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Vista general
Número de catálogoHB152137
Reactividad de especiesHuman
AplicacionesFCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonABT-007
ConjugaciónAPC
Objetivo EPOR, Erythropoietin receptor, EPO-R
Nivel de endotoxinas Please contact with the lab for this information.
Productos asociados Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Número de acceso P19235
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

1. Zhan, H. et al. (1999) Protein engineering 12, 505-13. PMID: 10388848
2. Winkelmann, JC. et al. (1990) Blood 76, 24-30. PMID: 2163695
3. Jones, SS. et al. (1990) Blood 76, 31-5. PMID: 2163696
4. Middleton, SA. et al. (1996) The Journal of biological chemistry 271, 14045-54. PMID: 8662939
5. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108
6. Kirito, K. et al. (2002) Blood 99, 102-10. PMID: 11756159
Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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