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Anti-Human Erythropoietin R Recombinant Antibody (ABT-007) (HB152107)

Anti-Human Erythropoietin R Recombinant Antibody (ABT-007)
Anti-Human Erythropoietin R Recombinant Antibody (ABT-007)
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  • 100ug
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Aperçu
Numéro de catalogueHB152107
Reactivité des espècesHuman
ApplicationsFCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneABT-007
Cible EPOR, Erythropoietin receptor, EPO-R
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P19235
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

1. Zhan, H. et al. (1999) Protein engineering 12, 505-13. PMID: 10388848
2. Winkelmann, JC. et al. (1990) Blood 76, 24-30. PMID: 2163695
3. Jones, SS. et al. (1990) Blood 76, 31-5. PMID: 2163696
4. Middleton, SA. et al. (1996) The Journal of biological chemistry 271, 14045-54. PMID: 8662939
5. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108
6. Kirito, K. et al. (2002) Blood 99, 102-10. PMID: 11756159
Note For research use only.
Images
  • Anti-Human Erythropoietin R Recombinant Antibody (ABT-007)

    SDS-PAGE

    SDS-PAGE for Anti-Human EPOR Antibody (ABT-007)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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