

| Каталожный номер | HS814107 |
|---|---|
| Реактивность видов | Human |
| Применения | FCM |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG2a |
| ID клона | mAb1479 |
| Цель | HER4, Tyrosine kinase-type cell surface receptor HER4, p180erbB4, s80HER4, ERBB4, 4ICD, Receptor tyrosine-protein kinase erbB-4, Proto-oncogene-like protein c-ErbB-4, E4ICD |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q15303 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Фон | Receptor tyrosine-protein kinase erbB-4 (ERBB4/Her4) is a ~146 kDa protein. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation. Required for normal development of the embryonic central nervous system, especially for normal neural crest cell migration and normal axon guidance. Required for mammary gland differentiation, induction of milk proteins and lactation. Acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. |
| Примечание | For research use only. |

SEC-HPLC detection for Anti-Human ERBB4/Her4 Antibody (mAb1479).




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