Anti-Human ERFE Recombinant Antibody (SAA1691) (HS700013)

Name: Anti-Human ERFE Recombinant Antibody (SAA1691)
Brand: abinScience
SKU: HS700013
Price: 110 USD
Availability: InStock

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Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HS700013

Описание

Anti-Human ERFE Recombinant Antibody (SAA1691) (HS700013) is a mouse monoclonal antibody detecting ERFE in ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1691

Цель

FAM132B, C1QTNF15, Erythroferrone, Complement C1q tumor necrosis factor-related protein 15, Myonectin, CTRP15, ERFE

Уровень эндотоксинов

< 10 EU/mg as determined by LAL method.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q4G0M1

RRID

Anti-Human ERFE Antibody (SAA1691) (abinScience Cat# HS700013, RRID:AB_3727452)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Erythroferrone (ERFE) is a ~37 kDa protein. Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. Inhibits apoptosis and inflammatory response in cardiomyocytes via promotion of sphingosine-1-phosphate (S1P) and cAMP-dependent activation of AKT signaling. Inhibits autophagy induced by nutrient deficiency in hepatocytes via promoting the phosphorylation of IRS1, AKT, and MTOR, and thereby subsequent activation of the AKT-MTOR signaling pathway. Negatively regulates the differentiation of osteoblasts, potentially via sequestering BMP2, and thereby inhibits the activation of SMAD signaling.

1. Kautz, L. et al. (2014) Nature genetics 46, 678-84. PMID: 24880340

2. Arezes, J. et al. (2018) Blood 132, 1473-1477. PMID: 30097509

3. Wang, CY. et al. (2020) Blood 135, 453-456. PMID: 31800957

Примечание

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human ERFE Antibody (SAA1691)

Ссылки

Даташит

Anti-Human ERFE Recombinant Antibody (SAA1691).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human ERFE Recombinant Antibody (SAA1691) (HS700013)

Обзор

Изображения

Ссылки

Даташит

SDS