Anti-Human ERLIN2 Polyclonal Antibody (HF861014)

Name: Anti-Human ERLIN2 Polyclonal Antibody
Brand: abinScience
SKU: HF861014
Price: 168 USD
Availability: InStock

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Prix(USD) : --

Spécification :

50ug
100ug

Nombre :

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF861014

Description

Anti-Human ERLIN2 Polyclonal Antibody (HF861014) is a rabbit polyclonal antibody detecting ERLIN2. Suitable for Rat, Mouse, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human ERLIN2 (Pro47-Asn339).

Cible

C8orf2, ERLIN2, Endoplasmic reticulum lipid raft-associated protein 2, Erlin-2, SPFH domain-containing protein 2, SPFH2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

O94905

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Erlin-2 (ERLIN2) is a ~37 kDa protein. Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.

1. Pearce, MM. et al. (2007) The Journal of biological chemistry 282, 20104-15. PMID: 17502376

2. Pearce, MM. et al. (2009) The Journal of biological chemistry 284, 10433-45. PMID: 19240031

3. Jo, Y. et al. (2011) The Journal of biological chemistry 286, 15022-31. PMID: 21343306

4. Huber, MD. et al. (2013) The Journal of cell biology 203, 427-36. PMID: 24217618

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human ERLIN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human ERLIN2 Polyclonal Antibody (HF861014)

Aperçu

Images

Reférences

Fiche technique

SDS