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Anti-Human EXTL3 Polyclonal Antibody (HD524014)

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Vista general
Número de catálogoHD524014
Descripción
Anti-Human EXTL3 Polyclonal Antibody (HD524014) is a rabbit polyclonal antibody detecting EXTL3. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human EXTL3 (Tyr341-Ile540).
Objetivo EC:2.4.1.223, EXT-related protein 1, EXTL1L, EXTL3, EXTR1, Exostosin-like 3, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, KIAA0519, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso O43909
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Exostosin-like 3 (EXTL3) is a ~104 kDa protein. Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Initiates HS synthesis by transferring the first N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) residue (GlcNAcT-I activity) to the tetrasaccharide linker (GlcA-Gal-Gal-Xyl-)Ser core linker. May also transfer alpha-GlcNAc residues during HS elongation (GlcNAcT-II activity). Lacks glucuronyl transferase II (GlcAT-II) activity. Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs).

1. Oud, MM. et al. (2017) American journal of human genetics 100, 281-296. PMID: 28132690
2. Volpi, S. et al. (2017) The Journal of experimental medicine 214, 623-637. PMID: 28148688
3. Kim, BT. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 7176-81. PMID: 11390981
4. Wilson, LFL. et al. (2022) Nature communications 13, 3314. PMID: 35676258
5. Lai, Y. et al. (2012) Immunity 37, 74-84. PMID: 22727489
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human EXTL3 Polyclonal Antibody

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