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Anti-Human FA2H Polyclonal Antibody (HP606014)

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Vista general
Número de catálogoHP606014
Descripción
Anti-Human FA2H Polyclonal Antibody (HP606014) is a rabbit polyclonal antibody detecting FA2H in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human FA2H (Ser12-Arg86).
Objetivo Fatty acid 2-hydroxylase, Fatty acid alpha-hydroxylase, FAXDC1, FAAH, FA2H, Fatty acid hydroxylase domain-containing protein 1
Purificación Purified by antigen affinity column.
Número de acceso Q7L5A8
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Fatty acid 2-hydroxylase (FA2H) is a ~42 kDa protein. Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. FA2H is stereospecific for the production of (R)-2-hydroxy fatty acids. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis.

1. Alderson, NL. et al. (2004) The Journal of biological chemistry 279, 48562-8. PMID: 15337768
2. Alderson, NL. et al. (2005) Journal of lipid research 46, 1569-75. PMID: 15863841
3. Uchida, Y. et al. (2007) The Journal of biological chemistry 282, 13211-9. PMID: 17355976
4. Guo, L. et al. (2012) Journal of lipid research 53, 1327-35. PMID: 22517924
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human FA2H Polyclonal Antibody

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