Anti-Human FA2H Polyclonal Antibody (HP606014)

Name: Anti-Human FA2H Polyclonal Antibody
Brand: abinScience
SKU: HP606014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HP606014

Description

Anti-Human FA2H Polyclonal Antibody (HP606014) is a rabbit polyclonal antibody detecting FA2H in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human FA2H (Ser12-Arg86).

Cible

Fatty acid 2-hydroxylase, Fatty acid alpha-hydroxylase, FAXDC1, FAAH, FA2H, Fatty acid hydroxylase domain-containing protein 1

Purification

Purified by antigen affinity column.

Numéro d'accès

Q7L5A8

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Fatty acid 2-hydroxylase (FA2H) is a ~42 kDa protein. Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. FA2H is stereospecific for the production of (R)-2-hydroxy fatty acids. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis.

1. Alderson, NL. et al. (2004) The Journal of biological chemistry 279, 48562-8. PMID: 15337768

2. Alderson, NL. et al. (2005) Journal of lipid research 46, 1569-75. PMID: 15863841

3. Uchida, Y. et al. (2007) The Journal of biological chemistry 282, 13211-9. PMID: 17355976

4. Guo, L. et al. (2012) Journal of lipid research 53, 1327-35. PMID: 22517924

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human FA2H Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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