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Anti-Human FAAH Polyclonal Antibody (HD694014)

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Aperçu
Numéro de catalogueHD694014
Description
Anti-Human FAAH Polyclonal Antibody (HD694014) is a rabbit polyclonal antibody detecting FAAH. Suitable for Human.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human FAAH (Ser71-Ser579).
Cible Anandamide amidohydrolase 1, EC:3.1.1.-, EC:3.5.1.99, FAAH, FAAH1, Fatty acid ester hydrolase, Fatty-acid amide hydrolase 1, Oleamide hydrolase 1
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès O00519
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Contexte

Fatty-acid amide hydrolase 1 (FAAH) is a ~63 kDa protein. Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol). FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids.

1. Wei, BQ. et al. (2006) The Journal of biological chemistry 281, 36569-78. PMID: 17015445
2. Kaczocha, M. et al. (2010) The Journal of biological chemistry 285, 2796-806. PMID: 19926788
3. Giang, DK. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 2238-42. PMID: 9122178
4. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human FAAH Polyclonal Antibody

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