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Anti-Human FABP5 Polyclonal Antibody (HX954014)

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Aperçu
Numéro de catalogueHX954014
Description
Anti-Human FABP5 Polyclonal Antibody (HX954014) is a rabbit polyclonal antibody detecting FABP5 in ELISA, IHC, WB. Suitable for Human and Bovine.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human FABP5 (Met1-Glu135).
Cible Psoriasis-associated fatty acid-binding protein homolog, FABP5, E-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein, epidermal, Fatty acid-binding protein 5, PA-FABP
Purification Purified by antigen affinity column.
Numéro d'accès Q01469
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Fatty acid-binding protein 5 (FABP5) is a ~15 kDa protein. Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation.

1. Mitchell, RW. et al. (2011) Journal of neurochemistry 117, 735-46. PMID: 21395585
2. Kaczocha, M. et al. (2012) The Journal of biological chemistry 287, 3415-24. PMID: 22170058
3. Siegenthaler, G. et al. (1994) The Biochemical journal 302 ( Pt 2), 363-71. PMID: 8092987
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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