Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188) (HC673013)

Name: Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188)
Brand: abinScience
SKU: HC673013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC673013

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IF, IP

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG

ID de clon

SAA0188

Objetivo

Fetal Alzheimer antigen, FALZ, Nucleosome-remodeling factor subunit BPTF, FAC1, BPTF, Fetal Alz-50 clone 1 protein, Bromodomain and PHD finger-containing transcription factor

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q12830

RRID

Anti-Human FALZ/BPTF IP Antibody (SAA0188) (abinScience Cat# HC673013, RRID:AB_3729722)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Nucleosome-remodeling factor subunit BPTF (FALZ) is a ~338 kDa protein. Regulatory subunit of the ATP-dependent NURF-1 and NURF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. The NURF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the NURF-5 ISWI chromatin remodeling complex. Within the NURF-1 ISWI chromatin-remodeling complex, binds to the promoters of En1 and En2 to positively regulate their expression and promote brain development. Histone-binding protein which binds to H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of active genes. Binds to histone H3 tails dimethylated on 'Lys-4' (H3K4Me2) to a lesser extent.

1. Barak, O. et al. (2003) The EMBO journal 22, 6089-100. PMID: 14609955

2. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535

3. Wysocka, J. et al. (2006) Nature 442, 86-90. PMID: 16728976

4. Li, H. et al. (2006) Nature 442, 91-5. PMID: 16728978

5. Li, H. et al. (2007) Molecular cell 28, 677-91. PMID: 18042461

6. Jordan-Sciutto, KL. et al. (1999) The Journal of biological chemistry 274, 35262-8. PMID: 10575013

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human FALZ/BPTF IP Antibody (SAA0188)

Referencias

Datasheet

Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo