Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188) (HC673013)

Name: Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188)
Brand: abinScience
SKU: HC673013
Price: 191 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HC673013

Реактивность видов

Human, Mouse

Применения

ELISA, IF, IP

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG

ID клона

SAA0188

Цель

Fetal Alzheimer antigen, FALZ, Nucleosome-remodeling factor subunit BPTF, FAC1, BPTF, Fetal Alz-50 clone 1 protein, Bromodomain and PHD finger-containing transcription factor

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q12830

RRID

Anti-Human FALZ/BPTF IP Antibody (SAA0188) (abinScience Cat# HC673013, RRID:AB_3729722)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Nucleosome-remodeling factor subunit BPTF (FALZ) is a ~338 kDa protein. Regulatory subunit of the ATP-dependent NURF-1 and NURF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. The NURF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the NURF-5 ISWI chromatin remodeling complex. Within the NURF-1 ISWI chromatin-remodeling complex, binds to the promoters of En1 and En2 to positively regulate their expression and promote brain development. Histone-binding protein which binds to H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of active genes. Binds to histone H3 tails dimethylated on 'Lys-4' (H3K4Me2) to a lesser extent.

1. Barak, O. et al. (2003) The EMBO journal 22, 6089-100. PMID: 14609955

2. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535

3. Wysocka, J. et al. (2006) Nature 442, 86-90. PMID: 16728976

4. Li, H. et al. (2006) Nature 442, 91-5. PMID: 16728978

5. Li, H. et al. (2007) Molecular cell 28, 677-91. PMID: 18042461

6. Jordan-Sciutto, KL. et al. (1999) The Journal of biological chemistry 274, 35262-8. PMID: 10575013

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human FALZ/BPTF IP Antibody (SAA0188)

Ссылки

Даташит

Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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