

| Каталожный номер | HF805014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human FAM20B Polyclonal Antibody (HF805014) is a rabbit polyclonal antibody detecting FAM20B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human FAM20B (Gln61-Leu409). | ||||||||
| Цель | Glycosaminoglycan xylosylkinase, 2.7.1.-, Xylose kinase, FAM20B, KIAA0475 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O75063 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Glycosaminoglycan xylosylkinase (FAM20B) is a ~46 kDa protein. Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized. | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-FAM20B polyclonal antibody at FAM20B on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse cerebellum lysate
Lane 3: Rat brain lysate
Lane 4: Rat cerebellum lysate
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