

| Numéro de catalogue | HD590014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FDPS Polyclonal Antibody (HD590014) is a rabbit polyclonal antibody detecting FDPS. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human FDPS (Asp74-Lys419). | ||||||||
| Cible | (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, EC:2.5.1.1, EC:2.5.1.10, FDPS, FPP synthase, FPS, Farnesyl diphosphate synthase, Farnesyl pyrophosphate synthase, Geranyltranstransferase, KIAA1293 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P14324 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Farnesyl pyrophosphate synthase (FDPS) is a ~48 kDa protein. Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-FDPS polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: Hela cell lysate
Lane 3: N2A cell lysate
Lane 4: NIH3T3 cell lysate
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