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Anti-Human FGF1/aFGF Recombinant Antibody (SAA0436) (HY232107)

Anti-Human FGF1/aFGF Recombinant Antibody (SAA0436)
Anti-Human FGF1/aFGF Recombinant Antibody (SAA0436)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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  • Vista general

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  • Datasheet

  • SDS

Vista general
Número de catálogoHY232107
Reactividad de especiesHuman
AplicacionesELISA, FCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA0436
Objetivo Endothelial cell growth factor, HBGF-1, Fibroblast growth factor 1, FGF1, ECGF, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, FGF-1, FGFA
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P05230
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Fibroblast growth factor 1 (FGF1/aFGF) is a ~17 kDa protein. Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3.

1. Mori, S. et al. (2008) The Journal of biological chemistry 283, 18066-75. PMID: 18441324
2. Yamaji, S. et al. (2010) PloS one 5, e10273. PMID: 20422052
3. Mori, S. et al. (2013) PloS one 8, e57927. PMID: 23469107
Nota For research use only.
Imágenes
  • Anti-Human FGF1/aFGF Recombinant Antibody (SAA0436)

    SDS-PAGE

    SDS-PAGE for Anti-Human FGF1/aFGF Antibody (SAA0436)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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