

| Numéro de catalogue | HC276014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FHL2 Polyclonal Antibody (HC276014) is a rabbit polyclonal antibody detecting FHL2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human FHL2 (Gly16-Ser98). | ||||||||
| Cible | DRAL, FHL2, LIM domain protein DRAL, FHL-2, Skeletal muscle LIM-protein 3, Four and a half LIM domains protein 2, SLIM-3, SLIM3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q14192 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Four and a half LIM domains protein 2 (FHL2) is a ~32 kDa protein. May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes. 1. Dierck, F. et al. (2017) The Journal of biological chemistry 292, 15180-15191. PMID: 28717008 | ||||||||
| Note | For research use only. |
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