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| カタログ番号 | HC469014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human FLII Polyclonal Antibody (HC469014) is a rabbit polyclonal antibody detecting FLII in ELISA, IHC, WB. Suitable for Mus musculus and Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human FLII (Leu896-Phe1176). | ||||||||
| ターゲット | FLII | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q13045 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | Protein flightless-1 homolog, FLII, FLIL | ||||||||
| 背景 | Protein flightless-1 homolog (FLII) is a ~144 kDa protein. Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. 1. Lee, YH. et al. (2004) Molecular and cellular biology 24, 2103-17. PMID: 14966289 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-FLII polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: A549 cell lysate
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