

| Каталожный номер | HB265195 |
|---|---|
| Описание |
Anti-Human FLT1/VEGFR1 Monoclonal Antibody (1A418) [1A418] (HB265195) is a mouse monoclonal antibody detecting VEGFR1 in ELISA. Suitable for Human.
|
| Реактивность видов | Human |
| Применения | ELISA |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG |
| ID клона | 1A418 |
| Иммуноген | Human FLT1/VEGFR1 Protein. |
| Цель | Vascular endothelial growth factor receptor 1, VEGFR-1, 2.7.10.1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor, FLT1, FLT, FRT, VEGFR1 |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P17948 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Vascular endothelial growth factor receptor 1 (FLT1/VEGFR1) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. 1. Lesslie, DP. et al. (2006) British journal of cancer 94, 1710-7. PMID: 16685275 |
| Примечание | For research use only. |

SDS-PAGE for Anti-Human FLT1/VEGFR1 Monoclonal Antibody (1A418)




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