Anti-Human VEGFR1/Flt-1 Monoclonal Antibody (1A419) (HB265205)

Name: Anti-Human VEGFR1/Flt-1 Monoclonal Antibody (1A419)
Brand: abinScience
SKU: HB265205
Price: 194 USD
Availability: InStock

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Número de catálogo	HB265205
Descripción	Anti-Human FLT1/VEGFR1 Monoclonal Antibody (1A419) [1A419] (HB265205) is a mouse monoclonal antibody detecting VEGFR1 in ELISA. Suitable for Human.
Reactividad de especies	Human
Aplicaciones	ELISA
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	1A419
Inmunógeno	Human FLT1/VEGFR1 Protein.
Objetivo	Vascular endothelial growth factor receptor 1, VEGFR-1, 2.7.10.1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor, FLT1, FLT, FRT, VEGFR1
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P17948
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Vascular endothelial growth factor receptor 1 (FLT1/VEGFR1) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. 1. Lesslie, DP. et al. (2006) British journal of cancer 94, 1710-7. PMID: 16685275
Nota	For research use only.