Anti-Human VEGFR1/Flt-1 Monoclonal Antibody (1A419) (HB265205)

Name: Anti-Human VEGFR1/Flt-1 Monoclonal Antibody (1A419)
Brand: abinScience
SKU: HB265205
Price: 194 USD
Availability: InStock

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Numéro de catalogue	HB265205
Description	Anti-Human FLT1/VEGFR1 Monoclonal Antibody (1A419) [1A419] (HB265205) is a mouse monoclonal antibody detecting VEGFR1 in ELISA. Suitable for Human.
Reactivité des espèces	Human
Applications	ELISA
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG
ID de clone	1A419
Immunogène	Human FLT1/VEGFR1 Protein.
Cible	Vascular endothelial growth factor receptor 1, VEGFR-1, 2.7.10.1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor, FLT1, FLT, FRT, VEGFR1
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P17948
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Vascular endothelial growth factor receptor 1 (FLT1/VEGFR1) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. 1. Lesslie, DP. et al. (2006) British journal of cancer 94, 1710-7. PMID: 16685275
Note	For research use only.