Anti-Human FMN2 Polyclonal Antibody (HD654014)

Name: Anti-Human FMN2 Polyclonal Antibody
Brand: abinScience
SKU: HD654014
Price: 168 USD
Availability: InStock

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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HD654014

Descripción

Anti-Human FMN2 Polyclonal Antibody (HD654014) is a rabbit polyclonal antibody detecting FMN2. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human FMN2 (Ser1361-Thr1722).

Objetivo

FMN2, Formin-2

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q9NZ56

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Fondo

Formin-2 (FMN2) is a ~180 kDa protein. Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest.

1. Vizcarra, CL. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 11884-9. PMID: 21730168

2. Peng, KW. et al. (2012) Biochimica et biophysica acta 1820, 469-81. PMID: 22330775

3. Yamada, K. et al. (2013) Molecular cell 49, 922-33. PMID: 23375502

4. Belin, BJ. et al. (2015) eLife 4, e07735. PMID: 26287480

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human FMN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo