

| Numéro de catalogue | HD564014 | ||||||||
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| Description |
Anti-Human FMO1 Polyclonal Antibody (HD564014) is a rabbit polyclonal antibody detecting FMO1. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human FMO1 (Met1-Pro510). | ||||||||
| Cible | Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, EC:1.14.13.148, EC:1.14.13.8, FMO 1, FMO1, Fetal hepatic flavin-containing monooxygenase 1, Flavin-containing monooxygenase 1, Trimethylamine monooxygenase | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q01740 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Flavin-containing monooxygenase 1 (FMO1) is a ~60 kDa protein. Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. 1. Veeravalli, S. et al. (2020) Drug metabolism and disposition: the biological fate of chemicals 48, 378-385. PMID: 32156684 | ||||||||
| Note | For research use only |
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