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Anti-Human FOLH1/PSMA Recombinant Antibody (J591), FITC (HC669117)

Anti-Human FOLH1/PSMA Recombinant Antibody (J591), FITC
Anti-Human FOLH1/PSMA Recombinant Antibody (J591), FITC
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概要
カタログ番号HC669117
種反応性Human
アプリケーションFCM
宿主種Human
クローン性Monoclonal
アイソタイプIgG1
クローンIDJ591
抱合FITC
テスト済みアプリケーション FCM
ターゲット NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP
エンドトキシンレベル Please contact with the lab for this information.
関連製品 Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC
アクセッション番号 Q04609
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Glutamate carboxypeptidase 2 (FOLH1/PSMA) is a ~84 kDa protein. Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.

参考文献 1. Schneider E, et al. Gamma-glutamyl hydrolase and drug resistance. Clin Chim Acta. 2006 Dec;374(1-2):25-32. [HC669117]
注意事項 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
イメージ
  • Anti-Human FOLH1/PSMA Recombinant Antibody (J591), FITC

    Flow CytoMetry

    Flow-cytometry using FITC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human FOLH1 monoclonal antibody (Catalog: HC669117, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

参考文献
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