

| Número de catálogo | HB721014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human FOLR2 Polyclonal Antibody (HB721014) is a rabbit polyclonal antibody detecting FOLR2/FR-β in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human FOLR2 (Thr17-Asn230). | ||||||||
| Objetivo | FBP, FOLR2, Folate receptor beta, Placental folate-binding protein, Folate receptor, fetal/placental, FR-beta, Folate receptor 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P14207 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Folate receptor beta (FOLR2/FR-β) is a ~29 kDa protein. Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. | ||||||||
| Nota | For research use only. |
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