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Anti-Human FOXP1 Polyclonal Antibody (HV703014)

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Anti-Human FOXP1 Polyclonal Antibody
Anti-Human FOXP1 Polyclonal Antibody
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Vista general
Número de catálogoHV703014
Descripción
Anti-Human FOXP1 Polyclonal Antibody (HV703014) is a rabbit polyclonal antibody detecting FOXP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human FOXP1 (Asn461-Pro671).
Objetivo FOXP1, MFH, Forkhead box protein P1, Mac-1-regulated forkhead
Purificación Purified by antigen affinity column.
Número de acceso Q9H334
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Forkhead box protein P1 (FOXP1) is a ~75 kDa protein. Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development.

1. Jepsen, K. et al. (2008) Genes & development 22, 740-5. PMID: 18347093
2. Sollis, E. et al. (2016) Human molecular genetics 25, 546-57. PMID: 26647308
3. van Keimpema, M. et al. (2014) Blood 124, 3431-40. PMID: 25267198
4. Shi, C. et al. (2004) The Journal of clinical investigation 114, 408-18. PMID: 15286807
5. Shi, C. et al. (2008) Blood 112, 4699-711. PMID: 18799727
6. Grundmann, S. et al. (2013) PloS one 8, e70873. PMID: 24023716
7. Takayama, K. et al. (2008) Biochemical and biophysical research communications 374, 388-93. PMID: 18640093
8. Kamran, M. et al. (2017) Oncogenesis 6, e298. PMID: 28218735
Nota For research use only.
Imágenes
  • Anti-Human FOXP1 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-FOXP1 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Jurkat cell lysate
    Lane 2: MCF-7 cell lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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