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Anti-Human FOXP1 Polyclonal Antibody (HV703014)

Anti-Human FOXP1 Polyclonal Antibody
Anti-Human FOXP1 Polyclonal Antibody
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  • 概要

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  • 参考文献

  • データシート

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概要
カタログ番号HV703014
説明
Anti-Human FOXP1 Polyclonal Antibody (HV703014) is a rabbit polyclonal antibody detecting FOXP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Human, Mouse, Rat
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Human FOXP1 (Asn461-Pro671).
ターゲット FOXP1, MFH, Forkhead box protein P1, Mac-1-regulated forkhead
精製 Purified by antigen affinity column.
アクセッション番号 Q9H334
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Forkhead box protein P1 (FOXP1) is a ~75 kDa protein. Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development.

1. Jepsen, K. et al. (2008) Genes & development 22, 740-5. PMID: 18347093
2. Sollis, E. et al. (2016) Human molecular genetics 25, 546-57. PMID: 26647308
3. van Keimpema, M. et al. (2014) Blood 124, 3431-40. PMID: 25267198
4. Shi, C. et al. (2004) The Journal of clinical investigation 114, 408-18. PMID: 15286807
5. Shi, C. et al. (2008) Blood 112, 4699-711. PMID: 18799727
6. Grundmann, S. et al. (2013) PloS one 8, e70873. PMID: 24023716
7. Takayama, K. et al. (2008) Biochemical and biophysical research communications 374, 388-93. PMID: 18640093
8. Kamran, M. et al. (2017) Oncogenesis 6, e298. PMID: 28218735
注意事項 For research use only.
イメージ
  • Anti-Human FOXP1 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-FOXP1 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Jurkat cell lysate
    Lane 2: MCF-7 cell lysate

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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