

| カタログ番号 | HV703014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human FOXP1 Polyclonal Antibody (HV703014) is a rabbit polyclonal antibody detecting FOXP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human FOXP1 (Asn461-Pro671). | ||||||||
| ターゲット | FOXP1, MFH, Forkhead box protein P1, Mac-1-regulated forkhead | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9H334 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Forkhead box protein P1 (FOXP1) is a ~75 kDa protein. Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. 1. Jepsen, K. et al. (2008) Genes & development 22, 740-5. PMID: 18347093 2. Sollis, E. et al. (2016) Human molecular genetics 25, 546-57. PMID: 26647308 3. van Keimpema, M. et al. (2014) Blood 124, 3431-40. PMID: 25267198 4. Shi, C. et al. (2004) The Journal of clinical investigation 114, 408-18. PMID: 15286807 5. Shi, C. et al. (2008) Blood 112, 4699-711. PMID: 18799727 6. Grundmann, S. et al. (2013) PloS one 8, e70873. PMID: 24023716 7. Takayama, K. et al. (2008) Biochemical and biophysical research communications 374, 388-93. PMID: 18640093 8. Kamran, M. et al. (2017) Oncogenesis 6, e298. PMID: 28218735 | ||||||||
| 注意事項 | For research use only. |

Western blot analysis was performed using anti-FOXP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: MCF-7 cell lysate


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