

| Каталожный номер | HV703014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human FOXP1 Polyclonal Antibody (HV703014) is a rabbit polyclonal antibody detecting FOXP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human FOXP1 (Asn461-Pro671). | ||||||||
| Цель | FOXP1, MFH, Forkhead box protein P1, Mac-1-regulated forkhead | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9H334 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Forkhead box protein P1 (FOXP1) is a ~75 kDa protein. Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. 1. Jepsen, K. et al. (2008) Genes & development 22, 740-5. PMID: 18347093 2. Sollis, E. et al. (2016) Human molecular genetics 25, 546-57. PMID: 26647308 3. van Keimpema, M. et al. (2014) Blood 124, 3431-40. PMID: 25267198 4. Shi, C. et al. (2004) The Journal of clinical investigation 114, 408-18. PMID: 15286807 5. Shi, C. et al. (2008) Blood 112, 4699-711. PMID: 18799727 6. Grundmann, S. et al. (2013) PloS one 8, e70873. PMID: 24023716 7. Takayama, K. et al. (2008) Biochemical and biophysical research communications 374, 388-93. PMID: 18640093 8. Kamran, M. et al. (2017) Oncogenesis 6, e298. PMID: 28218735 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-FOXP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: MCF-7 cell lysate
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