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| カタログ番号 | HA875013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1878 | ||||
| ターゲット | FXYD domain-containing ion transport regulator 5, FXYD5, DYSAD, Dysadherin, IWU1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q96DB9 | ||||
| RRID | Anti-Human FXYD5/dysadherin Antibody (SAA1878) (abinScience Cat# HA875013, RRID:AB_3727642) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | FXYD domain-containing ion transport regulator 5 (FXYD5/dysadherin) is a ~19 kDa protein. Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. May increase NKA activity by increasing the apparent affinity for Na(+). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis. 1. Miller, TJ. et al. (2008) American journal of physiology. Lung cellular and molecular physiology 294, L654-64. PMID: 18263667 2. Ino, Y. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 365-70. PMID: 11756660 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human FXYD5/dysadherin Antibody (SAA1878)
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