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Anti-Human FZD3/Frizzled-3 Recombinant Nanobody (SAA2319) (HC066023)

Anti-Human FZD3/Frizzled-3 Recombinant Nanobody (SAA2319)
Anti-Human FZD3/Frizzled-3 Recombinant Nanobody (SAA2319)
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Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoHC066023
Descripción
Anti-Human FZD3/Frizzled-3 Nanobody (SAA2319) [SAA2319] (HC066023) is a human monoclonal antibody detecting Frizzled-3 in ELISA. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoVHH-Fc
ID de clonSAA2319
Objetivo Frizzled-3, Fz-3, hFz3, FZD3
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9NPG1
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Frizzled-3 (FZD3) is a ~76 kDa protein. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Activation by Wnt5A stimulates PKC activity via a G-protein-dependent mechanism.

Nota For research use only
Imágenes
  • Anti-Human FZD3/Frizzled-3 Recombinant Nanobody (SAA2319)

    SDS-PAGE

    SDS-PAGE for Anti-Human FZD3/Frizzled-3 Nanobody (SAA2319)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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