Anti-Human GABARAPL1 Polyclonal Antibody (HP284014)

Name: Anti-Human GABARAPL1 Polyclonal Antibody
Brand: abinScience
SKU: HP284014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HP284014

Description

Anti-Human GABARAPL1 Polyclonal Antibody (HP284014) is a rabbit polyclonal antibody detecting GABARAPL1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Cavia porcellus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human GABARAPL1 (Met1-Lys117).

Cible

Early estrogen-regulated protein, Gamma-aminobutyric acid receptor-associated protein-like 1, GEC-1, GABARAPL1, Glandular epithelial cell protein 1, GEC1, GABA(A) receptor-associated protein-like 1

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9H0R8

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1) is a ~14 kDa protein. Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.

1. Chen, C. et al. (2006) The Journal of biological chemistry 281, 7983-93. PMID: 16431922

2. Chakrama, FZ. et al. (2010) Autophagy 6, 495-505. PMID: 20404487

3. An, H. et al. (2019) Molecular cell 74, 891-908.e10. PMID: 31006537

4. Chino, H. et al. (2019) Molecular cell 74, 909-921.e6. PMID: 31006538

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human GABARAPL1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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