Anti-Human GABARAPL1 Polyclonal Antibody (HP284014)

Name: Anti-Human GABARAPL1 Polyclonal Antibody
Brand: abinScience
SKU: HP284014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HP284014

Описание

Anti-Human GABARAPL1 Polyclonal Antibody (HP284014) is a rabbit polyclonal antibody detecting GABARAPL1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Cavia porcellus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human GABARAPL1 (Met1-Lys117).

Цель

Early estrogen-regulated protein, Gamma-aminobutyric acid receptor-associated protein-like 1, GEC-1, GABARAPL1, Glandular epithelial cell protein 1, GEC1, GABA(A) receptor-associated protein-like 1

Очистка

Purified by antigen affinity column.

Номер доступа

Q9H0R8

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1) is a ~14 kDa protein. Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.

1. Chen, C. et al. (2006) The Journal of biological chemistry 281, 7983-93. PMID: 16431922

2. Chakrama, FZ. et al. (2010) Autophagy 6, 495-505. PMID: 20404487

3. An, H. et al. (2019) Molecular cell 74, 891-908.e10. PMID: 31006537

4. Chino, H. et al. (2019) Molecular cell 74, 909-921.e6. PMID: 31006538

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human GABARAPL1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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