

| Каталожный номер | HX995014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human GABARAPL2 Polyclonal Antibody (HX995014) is a rabbit polyclonal antibody detecting GABARAPL2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human GABARAPL2 (Met1-Phe117). | ||||||||
| Цель | MAP1 light chain 3-related protein, GABA(A) receptor-associated protein-like 2, General protein transport factor p16, Ganglioside expression factor 2, GATE-16, GEF-2, GABARAPL2, Golgi-associated ATPase enhancer of 16 kDa, Gamma-aminobutyric acid receptor-associated protein-like 2, FLC3A, GEF2 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P60520 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) is a ~13 kDa protein. Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. 1. Weidberg, H. et al. (2010) The EMBO journal 29, 1792-802. PMID: 20418806 2. Zhu, Y. et al. (2013) The Journal of biological chemistry 288, 1099-113. PMID: 23209295 | ||||||||
| Примечание | For research use only. |
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