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| カタログ番号 | HP426014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GADD45GIP1 (Thr47-Ser222). | ||||||||
| ターゲット | CRIF1, GADD45GIP1, 39S ribosomal protein L59, mitochondrial, PLINP1, PLINP, MRP-L59, CKII beta-associating protein, Papillomavirus L2-interacting nuclear protein 1, PLINP-1, PRG6, CR6-interacting factor 1, MRPL59, p53-responsive gene 6 protein, Growth arrest and DNA damage-inducible proteins-interacting protein 1, Mitochondrial large ribosomal subunit protein mL64 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8TAE8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Large ribosomal subunit protein mL64 (GADD45GIP1) is a ~25 kDa protein. Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but also occur in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-GADD45GIP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: SKOV3 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: U251 cell lysate
Lane 4: Hela cell lysate
Lane 5: 293T cell lysate
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