

| Numéro de catalogue | HD530014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human GAR1 Polyclonal Antibody (HD530014) is a rabbit polyclonal antibody detecting GAR1. Suitable for Mouse, Rat, and Human.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human GAR1 (Val71-Arg160). | ||||||||
| Cible | GAR1, H/ACA ribonucleoprotein complex subunit 1, NOLA1, Nucleolar protein family A member 1, snoRNP protein GAR1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9NY12 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | H/ACA ribonucleoprotein complex subunit 1 (GAR1) is a ~22 kDa protein. Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. | ||||||||
| Note | For research use only |
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