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| カタログ番号 | HB017014 | ||||||||
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| 説明 |
Anti-Human GATA1 Polyclonal Antibody (HB017014) is a rabbit polyclonal antibody detecting GATA1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GATA1 (Ala211-Asp300). | ||||||||
| ターゲット | GATA-1, GF-1, NF-E1 DNA-binding protein, ERYF1, GF1, Erythroid transcription factor, GATA-binding factor 1, GATA1, Eryf1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P15976 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Erythroid transcription factor (GATA1) is a ~42 kDa protein. Transcriptional activator or repressor which serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS. 1. Ludwig, LS. et al. (2022) Blood 139, 2534-2546. PMID: 35030251 2. Mizuta, S. et al. (2014) Genes to cells : devoted to molecular & cellular mechanisms 19, 28-51. PMID: 24245781 | ||||||||
| 注意事項 | For research use only. |
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